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Signs and Symptoms

Signs and Symptoms

A few days after exposure, a low-grade fever, anorexia, malaise, and mouth soreness occurs. The fever, usually about 101°F, lasts a few days. Within a day or two, sores erupt in the mouth. They begin as tiny blisters on a red base that open up and resolve in a few days. Within a couple of days, small, clear to white blisters develop on the palms and soles. Similar lesions may develop on the rest of the skin. The characteristic oval blisters resolve within 1 week.


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    Original Date of Publication: 01 Sep 2000
    Reviewed by: Stanley J. Swierzewski, III, M.D.
    Last Reviewed: 04 Dec 2007

    Hand-Foot-and-Mouth Disease, Signs and Symptoms reprinted with permission from dermatologychannel.net
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    This page last modified: 25 Aug 2008

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