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Childhood Immunizations (Vaccinations)

Diphtheria, Tetanus, Pertussis (DTaP and Tdap) Vaccines

DTaP and Tdap vaccines protect against diphtheria, tetanus (lockjaw), and pertussis (whooping cough), which are serious bacterial infections. Diphtheria is a throat infection that can block the airway and lead to difficulty breathing, paralysis, and heart failure. Tetanus causes painful muscle tightening, paralysis, and seizures. Pertussis (whooping cough) causes severe coughing and can result in pneumonia, seizures, brain damage, and death.

The pertussis component of the vaccine can rarely cause seizures and should not be given to children who have seizure disorders, certain neurological diseases, or developmental problems.

Immunization schedule—DTaP vaccines usually are administered in 5 doses, as follows:

  • Dose 1 at 2 months of age
  • Dose 2 at 4 months of age
  • Dose 3 at 6 months of age
  • Dose 4 at 15-18 months of age
  • Dose 5 at 4-6 years of age (before entering school)

Booster shots include Tdap at 11-12 years of age, and then tetanus and diphtheria shots every 10 years.


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  • Physician-developed and -monitored.
    Original Date of Publication: 28 Aug 2008
    Reviewed by: Stanley J. Swierzewski, III, M.D.
    Last Reviewed: 17 Jun 2008

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